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The Moderna COVID-19 vaccine is a term used to describe multiple COVID-19 vaccine candidates and products developed by Moderna, primarily mRNA-1273.
As early as May 2021, SARS-CoV-2 spike proteins had been identified in blood samples taken from people who have been injected with mRNA-1273. This demonstrated that the antigens enter the bloodstream and circulate around the body for up to 15 days after the first dose.[1]
A study published in September 2022 found that circulating spike protein is associated with a wide range long-term symptoms broadly diagnosed as COVID-19.[2] Such symptoms include fatigue, shortness of breath, chest pain, cognitive disturbances, arthralgia and decline in quality of life[3] - all of which are known adverse events associated with mRNA-1273 and/or COVID-19 vaccines in general.[4][5][6]
Ogata, A. F., Cheng, C.-A., Desjardins, M., Senussi, Y., Sherman, A. C., Powell, M., Novack, L., Von, S., Li, X., Baden, L. R., & Walt, D. R. (2021). Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. Clinical Infectious Diseases, 74(4), 715–718. https://doi.org/10.1093/cid/ciab465 ↩︎
Swank, Z., Senussi, Y., Manickas-Hill, Z., Yu, X. G., Li, J. Z., Alter, G., & Walt, D. R. (2022). Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae. Clinical Infectious Diseases, 76(3), e487–e490. https://doi.org/10.1093/cid/ciac722 ↩︎
Nalbandian, A., Sehgal, K., Gupta, A., Madhavan, M. V., McGroder, C., Stevens, J. S., Cook, J. R., Nordvig, A. S., Shalev, D., Sehrawat, T. S., Ahluwalia, N., Bikdeli, B., Dietz, D., Der-Nigoghossian, C., Liyanage-Don, N., Rosner, G. F., Bernstein, E. J., Mohan, S., Beckley, A. A., & Seres, D. S. (2021). Post-acute COVID-19 syndrome. Nature Medicine, 27(4), 1–15. https://doi.org/10.1038/s41591-021-01283-z ↩︎
5.3.6 Cumulative Analysis of Post-authorization Adverse Event Reports. (2021). Public Health and Medical Professionals for Transparency; Pfizer. https://web.archive.org/web/20230714210336/https://phmpt.org/wp-content/uploads/2021/11/5.3.6-postmarketing-experience.pdf ↩︎
Yoshimura, Y., Sasaki, H., Miyata, N., Miyazaki, K., Koji Okudela, Tateishi, Y., Hayashi, H., Kawana-Tachikawa, A., Iwashita, H., Maeda, K., Ihama, Y., Yasuyoshi Hatayama, Akihide Ryo, & Natsuo Tachikawa. (2022). An autopsy case of COVID-19-like acute respiratory distress syndrome after mRNA-1273 SARS-CoV-2 vaccination. International Journal of Infectious Diseases, 121, P98-101. https://doi.org/10.1016/j.ijid.2022.04.057 ↩︎
Finsterer, J. (2022). A Case Report: Long Post-COVID Vaccination Syndrome During the Eleven Months After the Third Moderna Dose. Cureus, 14(12). https://doi.org/10.7759/cureus.32433 ↩︎